Closing the Evidence Gap Doctors, pharmacists, naturopaths, nurses, and other health professionals are able to write prescriptions within a regulatory framework identified by their professional organizations. All these bodies have remarkably similar approaches to prescribing as one might expect. They are based on recommendations set out...
As many as half of patients don’t take medications as prescribed, and 20% to 30% of prescriptions are never filled 1,2. This nonadherence to recommended treatment has dramatic effects on patients and the health care system. Lack of patient adherence leads to poor therapeutic outcomes...
Schizophrenia is a severe, chronic mental health condition characterized by a variety of psychological and psychotic symptoms. Some of these symptoms may include hallucinations, delusions, disordered thinking and changes in behavior. People with schizophrenia may have difficulty distinguishing their own thoughts and ideas from reality....
The decision to quit smoking is a big step to improving your health. It is never too late to quit and the benefits include a reduction in cancer, heart and lung disease, and improved quality of life. When attempting to quit smoking, both counseling and smoking cessation...
Ticagrelor (Brilinta, Brilique, and Possia) is a platelet aggregation inhibitor used after a heart attack to prevent clots from forming and causing further heart attacks. At this moment, there no clear evidence for the use of pharmacogenetics for ticagrelor. PharmGKB, a NIH-funded database that curates knowledge...
TreatGx is an evidence-based medication decision support system that provides personalized prescribing options for the management of common conditions. TreatGx logic trees include: 1. status of the condition being treated 2. previous non-pharmacological and pharmacological treatment(s) 3. current non-pharmacological and pharmacological treatment(s) 4. other diagnoses 5. pharmacogenetics 6. renal and hepatic function 7....
PharmGKB is a publicly available internet research tool that provides information about how genetic variation among individuals contributes to differences in reactions to drugs. Developed by Stanford University and funded by the National Institutes of Health (NIH), PharmGKB is the largest pharmacogenetic database. The information in...
The team at GenXys is excited to announce that Gastroesophageal Reflux Disease, H. pylori Eradication and Dyspepsia/Peptic Ulcer Disease are now covered by TreatGxPlus (pharmacogenetic test and decision support system). H. pylori Eradication Helicobacter pylori is a bacterium that infects your stomach. Most people don’t realize they...
The most up to date evidence does not support the use of SLC47A2 variants to predict glycemic response to metformin in diabetes Type 2 diabetes Type 2 diabetes is a chronic condition that affects the way the body metabolizes glucose (sugar) and is characterized by high levels...
The team at Genxys is excited to announce that Post-Myocardial Infarction (Heart Attack) and Smoking Cessation are now covered in TreatGxPlus (pharmacogenetic test and decision support system). Post-Myocardial Infarction (Heart Attack) A myocardial infarction (MI) is also known as a heart attack. This occurs when the heart...